I have noticed that one of the first things users want to do is to use the iPad for e-mail. Before you can check your e-mail you have to set up your iPad for your e-mail address and server.
It is not surprising that people want to use their e-mail first. So this movie covers how to set up an e-mail account using Gmail (although iCloud is similar). It then goes through the major parts of e-mail such as checking your e-mail, sending e-mails, replying to e-mails, deleting e-mails, and your e-mail settings.